Michigan Up Next | USC Trojans

Basic Info & Context

• USC’s 2025 schedule has the Michigan game slated for Saturday, October 11 in Los Angeles. (USC Athletics)

• The kickoff is set for 4:30 pm PT and it will be televised on NBC. (Yahoo Sports)

• This is one of USC’s marquee non-conference (or interconference) matchups under its new Big Ten alignment. (Maize n Brew)
  

What Makes This Game Interesting / Key Factors

Here are some of the elements that could decide the outcome:

Factor	How It Could Matter
Home Field	USC plays at home, which gives them crowd advantage, familiarity with the stadium, and less travel fatigue.
Quarterback Play & Execution	If Jayden Maiava (USC) plays efficiently, limits turnovers, and connects with his playmakers, USC will have a chance. Michigan will try to pressure him, force mistakes.
Continuity vs. Disruption	Michigan’s ability to disrupt USC’s timing (via pass rush, blitz, defensive line play) could throw off USC’s offense.
Depth & Injuries	USC has already had some injury concerns (especially on the OL and secondary). If Michigan exploits weaker positions, that could swing the game.
Big Plays & Momentum	Michigan will look for explosive plays (deep passes, big runs) to shift momentum. USC will need to answer in kind.
Third-Down Efficiency & Turnovers	In close games, converting on third downs and protecting the ball often makes the difference.
Coaching, Adjustments	Midgame adjustments (defensive scheme switches, offensive play-calling) will be critical, especially in the second half.

Also worth noting: Michigan is coming off a bye before this game, which could mean extra preparation time. (Maize n Brew)

Prediction & What I Expect

Given USC’s home advantage and strong offensive potential, I lean slightly toward USC in a close game. But Michigan is a formidable opponent, and if they can pressure USC’s QB or win the turnover battle, they could pull the upset.

Estimated Score Prediction: USC 31 – Michigan 27